SCHEMBL27348256

SCHEMBL27348256

O=Cc1cn(Cc2ncc(Cl)cn2)c(-c2ccc(Cl)s2)n1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 7/20 0.32
MAPK1 P28482 1/20 0.32
LMNA P02545 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
PTGS2 P35354 1/20 0.30
FBP1 P09467 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27348295 0.84
SCHEMBL27349314 0.81 CYP11B1 (0.33) GRIN2BMAPK1CYP11B1CYP11B2
SCHEMBL27348243 0.80 FBP1 (0.35) GRIN2BCYP11B1CYP11B2FBP1
SCHEMBL27348054 0.79 PTGS2 (0.33) GRIN2BCYP11B1CYP11B2PTGS2
SCHEMBL27348191 0.79 MEN1 (0.32) GRIN2BCYP11B1CYP11B2FBP1
SCHEMBL26088883 0.77 PTGS2 (0.37) LMNAPTGS2
SCHEMBL26093295 0.77 ALDH1A1 (0.38) GRIN2BMAPK1PTGS2
SCHEMBL27348240 0.76 NPSR1 (0.47) GRIN2BPTGS2
SCHEMBL26090572 0.74
SCHEMBL30720877 0.68 AGER (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543874-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS Syngenta Crop Protection AG (CH) 2025-04-30 EP disclosed
CN-119325472-A Herbicidal imidazole-containing compounds 先正达农作物保护股份公司 2025-01-17 CN disclosed
WO-2023247358-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-12-28 WO disclosed
WO-2023247358-A1 HERBICIDAL IMIDAZOLE-CONTAINING COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-12-28 WO disclosed