Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27347204 | 0.91 | AGTR1 (0.53) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL27319879 | 0.90 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL27398930 | 0.89 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL27408714 | 0.87 | AGTR2 (0.61) | AGTR1AGTR2 | |
| SCHEMBL7886323 | 0.87 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL27353031 | 0.86 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8560448 | 0.84 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL27365762 | 0.84 | AGTR1 (0.45) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL27411294 | 0.81 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL27409825 | 0.81 | AGTR2 (0.53) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051766-C | Angiotensin II antagonist imidazole derivatives, their preparation and their theapeutic use | SANKYO CO (JP) | 2000-04-26 | — | — | CN | disclosed |