Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840166 | 0.87 | TBXA2R (0.64) | ALDH1A1POLBMEN1KMT2ASGMS1 | |
| SCHEMBL25246484 | 0.84 | TSHR (0.67) | ALDH1A1MAPK1POLBTP53TSHR | |
| SCHEMBL10463536 | 0.82 | CYP19A1 (0.68) | ALDH1A1MAPK1HSD17B10POLBMEN1 | |
| SCHEMBL9661154 | 0.80 | SGMS1 (0.62) | ALDH1A1MAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL25245661 | 0.80 | TSHR (0.64) | ALDH1A1POLBMEN1KMT2ATP53 | |
| SCHEMBL1169525 | 0.80 | POLB (0.65) | ALDH1A1MAPK1HSD17B10POLBMEN1 | |
| SCHEMBL6271065 | 0.78 | ALDH1A1 (0.66) | ALDH1A1MAPK1HSD17B10POLBMEN1 | |
| SCHEMBL1287434 | 0.78 | ALDH1A1 (0.70) | ALDH1A1MAPK1HSD17B10POLBMEN1 | |
| SCHEMBL10205710 | 0.78 | ALDH1A1 (0.66) | ALDH1A1MAPK1HSD17B10POLBMEN1 | |
| SCHEMBL5960116 | 0.78 | MEN1 (0.73) | ALDH1A1MAPK1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045780-A | The preparation of new sulfonamide derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1990-10-03 | — | — | CN | disclosed |