SCHEMBL2734974

SCHEMBL2734974

CCC(C)(C)C(=O)NC(C)C(=O)OCOC

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.38
METAP2 P50579 2/20 0.34
METAP1 P53582 2/20 0.34
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
BIRC2 Q13490 1/20 0.32
TSHR P16473 1/20 0.32
MMP8 P22894 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14649802 0.79 RIPK1 (0.37) RIPK1METAP2METAP1TSHRMMP8
SCHEMBL2734967 0.78 METAP2 (0.37) RIPK1METAP2
SCHEMBL20047507 0.74 RIPK1 (0.47) RIPK1TSHR
SCHEMBL14649798 0.74 RIPK1 (0.36) RIPK1METAP2METAP1MMP8
SCHEMBL25748849 0.73 RIPK1 (0.42) RIPK1MEN1KMT2AMMP8
SCHEMBL749946 0.72 RIPK1 (0.47) RIPK1MEN1KMT2ATSHRMMP8
SCHEMBL18681250 0.72 RIPK1 (0.45) RIPK1
SCHEMBL18681666 0.70 RIPK1 (0.41) RIPK1
SCHEMBL47526 0.70 CYP4F2 (0.37)
SCHEMBL23175981 0.69 RIPK1 (0.42) RIPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088550-B2 Positive resist composition and pattern forming method FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-20090035692-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING MEHTOD FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20090023096-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2009-01-22 US disclosed