SCHEMBL749946

SCHEMBL749946

CCC(C)(C)C(=O)NC(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 4/20 0.47
MEN1 O00255 1/20 0.38
FAAH O00519 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
CCR2 P41597 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
EPHX1 P07099 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 3/20 0.35
LMNA P02545 2/20 0.35
CYP3A4 P08684 1/20 0.35
NFKB1 P19838 1/20 0.35
ADRA1A P35348 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
POLB P06746 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24458985 0.83 SIGMAR1 (0.37) RIPK1MEN1FAAHMAPK1KMT2A
SCHEMBL15083020 0.82 MMP1 (0.45) RIPK1MEN1KMT2AEPHX1ALDH1A1
SCHEMBL15894960 0.82 MMP1 (0.45) RIPK1MEN1KMT2AEPHX1ALDH1A1
SCHEMBL618916 0.81 SIGMAR1 (0.36) RIPK1MEN1FAAHMAPK1KMT2A
SCHEMBL20047507 0.80 RIPK1 (0.47) RIPK1FAAHALDH1A1TSHRRAB9A
SCHEMBL18653409 0.79 MMP8 (0.39) RIPK1MEN1FAAHMAPK1KMT2A
SCHEMBL10170223 0.79 SIGMAR1 (0.35) RIPK1MEN1FAAHMAPK1KMT2A
SCHEMBL15895098 0.79 RIPK1 (0.42) RIPK1MEN1FAAHMAPK1KMT2A
SCHEMBL19449732 0.79 RIPK1 (0.42) RIPK1CCR2ALDH1A1LMNACYP3A4
SCHEMBL23175981 0.79 RIPK1 (0.42) RIPK1MEN1FAAHMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-11833237-B2 Method for enhancing scalp active deposition THE PROCTER & GAMBLE COMPANY (US) 2023-12-05 US disclosed
US-20230330659-A1 SUBSTRATE WITH ORTHOGONALLY FUNCTIONAL NANODOMAINS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-10-19 US disclosed
US-11771635-B2 Shampoo composition THE PROCTER & GAMBLE COMPANY (US) 2023-10-03 US disclosed
US-20230288623-A1 OPTICAL FILM, OPTICAL LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
US-11745531-B2 Printing plate precursor, printing plate precursor laminate, method for making printing plate, and printing method FUJIFILM CORPORATION (JP) 2023-09-05 US disclosed
US-20230270883-A1 ACTIVE AGENT RELEASE PARTICLE OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-08-31 US disclosed
US-20230265346-A1 LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-08-24 US disclosed
US-20230213823-A1 LIGHT ABSORPTION ANISOTROPIC FILM, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 US disclosed
US-7314698-B2 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2008-01-01 US disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070141513-A1 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-06-21 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-7214465-B2 Positive photosensitive composition FUJIFILM CORPORATION (JP) 2007-05-08 US disclosed
US-7192681-B2 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 2007-03-20 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
US-5846990-A Substituted biphenyl isoxazole sulfonamides BRISTOL-MYERS SQUIBB CO. (US) 1998-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11833237-B2 Method for enhancing scalp active deposition POLR1C, PRKDC, CUTA RIPK1 4085/4885MEN1 167/4885FAAH 3368/4885
US-20230270883-A1 ACTIVE AGENT RELEASE PARTICLE AIFM2, ACR, SLC40A1 RIPK1 2382/4885MEN1 569/4885FAAH 1900/4885
US-11771635-B2 Shampoo composition PSAP, SGMS2, ALG1 RIPK1 3490/4885MEN1 1706/4885FAAH 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.