Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1479730 | 0.74 | LMNA (0.55) | LMNAHSP90AA1KDM4ENAPRTHCAR2 | |
| SCHEMBL8300321 | 0.74 | LMNA (0.39) | LMNAKDM4ESMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7437060 | 0.72 | ADORA3 (0.50) | LMNAHSP90AA1KDM4ENAPRTHCAR2 | |
| SCHEMBL27943985 | 0.72 | BAZ2B (0.50) | LMNAHSP90AA1KDM4ENAPRTHCAR2 | |
| SCHEMBL1617422 | 0.72 | — | — | |
| SCHEMBL8083497 | 0.72 | — | — | |
| SCHEMBL15516303 | 0.71 | LMNA (0.45) | LMNAHSP90AA1KDM4ENAPRTHCAR2 | |
| SCHEMBL7211340 | 0.71 | LMNA (0.45) | LMNAHSP90AA1KDM4ENAPRTHCAR2 | |
| SCHEMBL22327277 | 0.68 | — | — | |
| SCHEMBL3504579 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043887-C | Chemically resistant compounds, their preparation and use | KIM NAK DOO (KR) | 1999-06-30 | — | — | CN | claimed |
| CN-1115981-A | New chemopreventive compounds and a preparation method and use thereof | WON KEUN CHUNG (KR) | 1996-01-31 | — | — | CN | claimed |
| CN-1043887-C | Chemically resistant compounds, their preparation and use | KIM NAK DOO (KR) | 1999-06-30 | — | — | CN | disclosed |
| CN-1115981-A | New chemopreventive compounds and a preparation method and use thereof | WON KEUN CHUNG (KR) | 1996-01-31 | — | — | CN | disclosed |