Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27409781 | 1.00 | CA12 (0.44) | CA12CA9ALOX15HSD17B10GAA | |
| SCHEMBL24455245 | 1.00 | CA12 (0.44) | CA12CA9ALOX15HSD17B10GAA | |
| SCHEMBL27406950 | 1.00 | CA12 (0.44) | CA12CA9ALOX15HSD17B10GAA | |
| SCHEMBL21602736 | 0.83 | ALOX15 (0.53) | CA12CA9ALOX15HSD17B10GAA | |
| Dihydrophenanthridine SCHEMBL29791568 | 0.78 | CA12 (0.56) | CA12CA9ALOX15HSD17B10GAA | |
| Dihydrophenanthridine SCHEMBL2087461 | 0.78 | CA12 (0.56) | CA12CA9ALOX15HSD17B10GAA | |
| SCHEMBL27425414 | 0.77 | CA12 (0.54) | CA12CA9ALOX15HSD17B10GAA | |
| SCHEMBL11774761 | 0.74 | LRRK2 (0.46) | ALOX15GAATSHRMAOAMAOB | |
| SCHEMBL17901678 | 0.74 | ALOX15 (0.47) | CA12CA9ALOX15HSD17B10GAA | |
| SCHEMBL30118299 | 0.74 | NOS2 (0.43) | CA12CA9ALOX15HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133815-A1 | ANTIBODY-DRUG CONJUGATES WITH MASKED PBD DIMERS | SYNAFFIX B.V. (NL) | 2024-06-27 | — | — | WO | disclosed |