Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30696747 | 1.00 | MAPT (0.43) | MAPTGAAKDM4ENR3C1PGR | |
| SCHEMBL27354572 | 0.74 | MAPT (0.49) | MAPTGAAKDM4ENR3C1PGR | |
| SCHEMBL27354573 | 0.72 | ALDH1A1 (0.45) | MAPTGAAKDM4ENR3C1PGR | |
| SCHEMBL30696827 | 0.71 | MAOA (0.43) | MAPTGAAKDM4ENR3C1PGR | |
| SCHEMBL30696787 | 0.69 | BCHE (0.42) | MAPTGAAKDM4ENR3C1PGR | |
| SCHEMBL27356784 | 0.69 | BCHE (0.42) | MAPTGAAKDM4ENR3C1PGR | |
| SCHEMBL27354577 | 0.67 | PPARA (0.37) | KDM4EALDH1A1 | |
| SCHEMBL27354578 | 0.66 | PPARA (0.36) | GAAKDM4EALDH1A1 | |
| SCHEMBL31409464 | 0.65 | ALDH1A1 (0.51) | GAAALDH1A1 | |
| SCHEMBL6087830 | 0.65 | MAPT (0.52) | MAPTGAAKDM4ENR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006742-A2 | NRF2 PROTEIN DEGRADERS | DRACEN PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |