SCHEMBL27355083

SCHEMBL27355083

NC(=O)c1ccc2cccoc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.42
BCAT2 O15382 1/20 0.41
IKBKB O14920 1/20 0.41
MAPT P10636 3/20 0.39
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPK10 P53779 1/20 0.39
MKNK1 Q9BUB5 3/20 0.38
MKNK2 Q9HBH9 3/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CDC7 O00311 1/20 0.38
KDM4E B2RXH2 3/20 0.37
HSD17B10 Q99714 2/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
POLB P06746 1/20 0.37
CASP1 P29466 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27300806 0.98 ADORA2A (0.41) ADORA2ABCAT2IKBKBMAPTALDH1A1
SCHEMBL5177213 0.85 ADORA2A (0.50) ADORA2ABCAT2IKBKBMAPTALDH1A1
SCHEMBL7869896 0.82 ACMSD (0.44) ALDH1A1KMT2ACES2CES1KDM4E
SCHEMBL8315867 0.78 ALDH1A1 (0.43) IKBKBMAPTALDH1A1KMT2ACDC7
SCHEMBL38652499 0.76 ALDH1A1 (0.39) MAPTALDH1A1KMT2AMAPK10CES2
SCHEMBL6586086 0.74 IKBKB (0.50) ADORA2ABCAT2IKBKBMKNK1MKNK2
SCHEMBL1981395 0.71 ALDH1A1 (0.47) BCAT2MAPTALDH1A1KMT2AMAPK10
SCHEMBL11699968 0.71 IKBKB (0.36) ADORA2ABCAT2IKBKBMAPTALDH1A1
SCHEMBL30733354 0.70 POLB (0.37) ADORA2ABCAT2MAPTALDH1A1KDM4E
SCHEMBL27624326 0.69 ACMSD (0.47) MAPTALDH1A1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1071332-C Enterokinetic benzamide JANSSEN PHARMACEUTICA NV (BE) 2001-09-19 CN disclosed
CN-1164233-A Enterokinetic benzamide JANSSEN PHARMACEUTICA NV (BE) 1997-11-05 CN disclosed