Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295572 | 0.88 | HTT (0.44) | HTTDNM1USP2 | |
| SCHEMBL27255116 | 0.87 | S1PR2 (0.35) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL2401504 | 0.86 | HTT (0.43) | HTTDNM1USP2 | |
| SCHEMBL26925526 | 0.81 | SPHK1 (0.40) | HTTDNM1USP2 | |
| SCHEMBL3237751 | 0.79 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL8990536 | 0.78 | USP2 (0.43) | ALDH1A1HTTDNM1USP2 | |
| SCHEMBL28071184 | 0.78 | HTT (0.42) | HTTDNM1USP2 | |
| SCHEMBL1289353 | 0.75 | TSHR (0.56) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL11879340 | 0.74 | DNM1 (0.43) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL21828343 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRS1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250375-A1 | CIRCULAR RNA ENCODING CHIMERIC ANTIGEN RECEPTORS TARGETING BCMA | ORNA THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |