Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 11/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27355375 | 0.86 | SCN9A (0.44) | SCN9ACYP11B1CYP11B2EGLN2CCNT1 | |
| SCHEMBL31673746 | 0.83 | MAOA (0.37) | SCN9AALPL | |
| SCHEMBL27355360 | 0.77 | SCN9A (0.47) | SCN9ACYP11B1CYP11B2CCNT1CDK9 | |
| SCHEMBL26517604 | 0.77 | UGCG (0.39) | SCN9A | |
| SCHEMBL30876888 | 0.75 | SCN9A (0.38) | SCN9ACYP11B1CYP11B2CCNT1CDK9 | |
| SCHEMBL25857355 | 0.74 | PIP4K2A (0.30) | — | |
| SCHEMBL26516215 | 0.72 | MGAT2 (0.41) | CYP11B1CYP11B2CHUK | |
| SCHEMBL25854611 | 0.71 | EP300 (0.37) | — | |
| SCHEMBL30108683 | 0.71 | PDE5A (0.46) | SCN9ACYP11B1CYP11B2EGLN2PLAU | |
| SCHEMBL30108822 | 0.71 | AR (0.43) | SCN9ACYP11B1CYP11B2EGLN2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141535-A1 | NLRP3 INFLAMMASOME INHIBITORS | ASTRAZENECA AB (SE) | 2024-07-04 | — | — | WO | disclosed |