Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27382274 | 0.84 | CHRM4 (0.39) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL27452402 | 0.83 | CHRM4 (0.38) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL27364630 | 0.83 | CHRM4 (0.38) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL27531812 | 0.82 | MEN1 (0.42) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL27377273 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL7794556 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8862704 | 0.80 | LTB4R (0.46) | ALDH1A1HSD17B10CHRM4LTB4R | |
| SCHEMBL27379780 | 0.80 | SLC2A1 (0.47) | ALDH1A1HSD17B10LTB4R | |
| SCHEMBL9094776 | 0.79 | LTB4R (0.41) | ALDH1A1HSD17B10LMNACHRM4LTB4R | |
| SCHEMBL7794741 | 0.79 | CHRM4 (0.42) | ALDH1A1HSD17B10MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071164-A | Nitrogen-containing heterocycle compound | EISAI CO LTD (JP) | 1993-04-21 | — | — | CN | disclosed |