Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794333 | 0.89 | KMT2A (0.45) | CHRM4LTB4RALDH1A1KDM4EMAPT | |
| SCHEMBL7797440 | 0.85 | HSP90AB1 (0.40) | CHRM4LTB4RSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7797896 | 0.83 | HSP90AB1 (0.51) | CHRM4LTB4RALDH1A1HSP90AB1HSD17B10 | |
| SCHEMBL8862704 | 0.81 | LTB4R (0.46) | CHRM4LTB4RALDH1A1IGFBP3HSP90AB1 | |
| SCHEMBL27379780 | 0.81 | SLC2A1 (0.47) | LTB4RALDH1A1HSP90AB1HSD17B10 | |
| SCHEMBL9094776 | 0.80 | LTB4R (0.41) | CHRM4LTB4RALDH1A1LMNAIGFBP3 | |
| SCHEMBL27355398 | 0.79 | ALDH1A1 (0.43) | CHRM4LTB4RSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27382274 | 0.76 | CHRM4 (0.39) | CHRM4LTB4RALDH1A1KDM4EMAPT | |
| SCHEMBL149749 | 0.75 | PDE4A (0.57) | LTB4RSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL7794732 | 0.75 | PDE4A (0.49) | LTB4RSMN1; SMN2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031760-A1 | Method of treating a patient having precancerous lesions with quinazoline derivatives | PAMUKCU RIFAT (US) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031760-A1 | Method of treating a patient having precancerous lesions with quinazoline derivatives | MKI67, PCNA, NQO2 | CHRM4 3789/4885LTB4R 1536/4885SMN1; SMN2 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.