Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27355402 | 0.79 | EGFR (0.44) | KDM4ECA2 | |
| SCHEMBL2821323 | 0.76 | GAA (0.49) | CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL10701749 | 0.74 | PTGER3 (0.53) | KDM4EALDH1A1 | |
| SCHEMBL30447349 | 0.74 | PTGER3 (0.53) | KDM4EALDH1A1 | |
| SCHEMBL1115081 | 0.71 | CA2 (0.52) | KDM4EALDH1A1CA2 | |
| SCHEMBL29718749 | 0.71 | CA2 (0.52) | KDM4EALDH1A1CA2 | |
| SCHEMBL4149984 | 0.69 | CA2 (0.53) | KDM4EALDH1A1CA2 | |
| SCHEMBL16929918 | 0.69 | CYP4F2 (0.40) | CYP4F2CYP4A11KDM4E | |
| SCHEMBL3690475 | 0.68 | CSNK2A1 (0.41) | CYP4F2CYP4A11 | |
| SCHEMBL19706678 | 0.68 | ALDH1A1 (0.38) | CXCL12CYP4F2CYP4A11KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006742-A2 | NRF2 PROTEIN DEGRADERS | DRACEN PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |