Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27355404 | 0.79 | CXCL12 (0.38) | CA2KDM4E | |
| SCHEMBL12518688 | 0.78 | EGFR (0.53) | EGFRITKBCHECNR2ADRB2 | |
| SCHEMBL25815777 | 0.77 | EGFR (0.47) | EGFRITKBCHECNR2ADRB2 | |
| SCHEMBL28710981 | 0.76 | L3MBTL1 (0.46) | — | |
| SCHEMBL926197 | 0.75 | SCN9A (0.46) | EGFRITKCA12CA1CA2 | |
| SCHEMBL25815595 | 0.74 | EGFR (0.51) | EGFRITKBCHECNR2ADRB2 | |
| SCHEMBL3686366 | 0.74 | GRM2 (0.48) | — | |
| SCHEMBL1667818 | 0.74 | BCHE (0.44) | EGFRITKBCHECNR2ADRB2 | |
| SCHEMBL13883179 | 0.74 | BCHE (0.47) | EGFRITKBCHECNR2ADRB2 | |
| SCHEMBL31500921 | 0.73 | TTR (0.50) | CA12CA1CA2CA9SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006742-A2 | NRF2 PROTEIN DEGRADERS | DRACEN PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |