SCHEMBL2735596

SCHEMBL2735596

CC(=O)Nc1cc(NC(C)=O)cc(C(=O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.56
KMT2A Q03164 7/20 0.56
LMNA P02545 1/20 0.56
NAPRT Q6XQN6 1/20 0.52
HSD17B10 Q99714 1/20 0.52
L3MBTL1 Q9Y468 4/20 0.52
PKM P14618 1/20 0.52
POLB P06746 2/20 0.52
GAA P10253 2/20 0.47
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL618917 0.95 L3MBTL1 (0.57) MEN1KMT2ALMNANAPRTHSD17B10
SCHEMBL10148977 0.88 TPMT (0.59) MEN1KMT2ALMNANAPRTHSD17B10
SCHEMBL21855109 0.86 L3MBTL1 (0.53) MEN1KMT2ALMNANAPRTHSD17B10
SCHEMBL5108982 0.86 ALDH1A1 (0.53) MEN1KMT2ALMNANAPRTHSD17B10
SCHEMBL29152083 0.86 LMNA (0.47) MEN1KMT2ALMNANAPRTHSD17B10
SCHEMBL16397403 0.86 MEN1 (0.53) MEN1KMT2ALMNANAPRTHSD17B10
SCHEMBL3071609 0.85 LMNA (0.71) MEN1KMT2ALMNANAPRTHSD17B10
SCHEMBL13229315 0.85 KDM4E (0.56) MEN1KMT2ALMNAHSD17B10L3MBTL1
SCHEMBL11930067 0.83 ALDH1A1 (0.50) MEN1KMT2ALMNANAPRTHSD17B10
SCHEMBL29954272 0.83 PDE3B (0.46) MEN1KMT2ALMNANAPRTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
CN-114478295-A Method for synthesizing diatrizoic acid 浙江海洲制药有限公司 2022-05-13 CN disclosed
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US disclosed
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US disclosed
US-20180030246-A1 COMPOSITION AND MOLDED ARTICLE AKITA UNIVERSITY (JP) 2018-02-01 US disclosed
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US disclosed
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US disclosed
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2012-03-01 US disclosed
US-8088884-B2 Multi-armed forms of activated polyoxazoline and methods of synthesis thereof SERINA THERAPEUTICS, INC. (US) 2012-01-03 US disclosed
US-20100249368-A1 Multi-Armed Forms of Activated Polyoxazoline and Methods of Synthesis Thereof SERINA THERAPEUTICS, INC. (US) 2010-09-30 US disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
EP-0620490-B1 Silver halide light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-09-01 EP disclosed
EP-0903633-A1 Heat-developable color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1999-03-24 EP disclosed
US-5585231-A DISPERSE DYES IN PHOTOGRAPHIC FILMS FUJI PHOTO FILM CO., LTD. (JP) 1996-12-17 US disclosed
US-5543279-A SMALL FLUCTUATION IN SENSITIVITY WITH TEMPERATURE CHANGE FUJI PHOTO FILM CO., LTD. (JP) 1996-08-06 US disclosed
US-5362843-A Phenyl branching agents HOECHST CELANESE CORPORATION (US) 1994-11-08 US disclosed
EP-0620491-A1 Heat developable color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1994-10-19 EP disclosed
EP-0620490-A1 Silver halide light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1994-10-19 EP disclosed
US-4243653-A Non-ionic polyiodo sugar substituted anilines THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1981-01-06 US disclosed
US-3991105-A CHEMICAL INTERMEDIATES FOR X-RAY CONTRAST AGENTS NYEGAARD & CO. A/S (NO) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 MEN1 698/4885KMT2A 964/4885LMNA 3479/4885
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 MEN1 698/4885KMT2A 964/4885LMNA 3479/4885
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 MEN1 698/4885KMT2A 964/4885LMNA 3479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.