Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19773643 | 0.88 | ANPEP (0.48) | SMN1; SMN2HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL1832075 | 0.87 | PPARG (0.55) | SMN1; SMN2TDP1HDAC8ANPEPCYP1A2 | |
| SCHEMBL25187228 | 0.86 | CYP1A2 (0.55) | SMN1; SMN2TDP1HDAC8ANPEPCYP1A2 | |
| SCHEMBL7293687 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2ANPEPCYP1A2ALDH1A1MEN1 | |
| SCHEMBL4992960 | 0.81 | CYP1A2 (0.66) | ANPEPCYP1A2PPARGSLC1A1CPA3 | |
| SCHEMBL13355067 | 0.78 | DNM1 (0.53) | TDP1ANPEPCYP1A2ALDH1A1MEN1 | |
| SCHEMBL13355018 | 0.78 | DNM1 (0.53) | TDP1ANPEPCYP1A2ALDH1A1MEN1 | |
| SCHEMBL15101698 | 0.78 | DNM1 (0.53) | TDP1ANPEPCYP1A2ALDH1A1MEN1 | |
| SCHEMBL20037882 | 0.78 | CHRM1 (0.38) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL4550704 | 0.78 | CYP1A2 (0.70) | HDAC1HDAC2CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053472-C | Oligonucleotides derived from the SOD family | HOFFMANN LA ROCHE (CH) | 2000-06-14 | — | — | CN | disclosed |
| CN-1106405-A | Trisubstituted pyrimido [5,4-d] pyrimidines for modulating | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | CN | disclosed |