Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30685026 | 0.97 | SIRT2 (0.52) | SIRT2FOLH1MMP2MMP9DPP8 | |
| SCHEMBL27356568 | 0.86 | SIRT2 (0.48) | SIRT2FOLH1MMP2MMP9DPP8 | |
| SCHEMBL30685198 | 0.79 | DPP8 (0.59) | DPP8 | |
| SCHEMBL27356370 | 0.79 | DPP8 (0.59) | DPP8 | |
| SCHEMBL26212052 | 0.78 | DPP8 (0.49) | SIRT2FOLH1MMP2MMP9DPP8 | |
| SCHEMBL27356105 | 0.76 | DPP8 (0.69) | DPP8 | |
| SCHEMBL30685134 | 0.76 | DPP8 (0.69) | DPP8 | |
| SCHEMBL31679031 | 0.76 | DPP8 (0.51) | SIRT2FOLH1MMP2MMP9DPP8 | |
| SCHEMBL30341837 | 0.75 | KLK7 (0.54) | SIRT2CTSLKLK7KLK5 | |
| SCHEMBL22117406 | 0.75 | SIRT2 (0.50) | SIRT2FOLH1MMP2MMP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023233024-A1 | DPP9 BINDING COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2023-12-07 | — | — | WO | disclosed |