Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | TGM2 | P21980 | 4/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27356571 | 0.97 | SIRT2 (0.50) | SIRT2CTSLFOLH1TGM2F13A1 | |
| SCHEMBL27356568 | 0.82 | SIRT2 (0.48) | SIRT2CTSLFOLH1TGM2F13A1 | |
| SCHEMBL26212052 | 0.76 | DPP8 (0.49) | SIRT2CTSLFOLH1MMP2MMP9 | |
| SCHEMBL27356370 | 0.76 | DPP8 (0.59) | DPP8DPP9 | |
| SCHEMBL30685198 | 0.76 | DPP8 (0.59) | DPP8DPP9 | |
| SCHEMBL5332693 | 0.74 | SIRT2 (0.65) | SIRT2CTSLFOLH1SIRT1SIRT5 | |
| SCHEMBL5332690 | 0.74 | SIRT2 (0.65) | SIRT2CTSLFOLH1SIRT1SIRT5 | |
| SCHEMBL31679031 | 0.74 | DPP8 (0.51) | SIRT2CTSLFOLH1MMP2MMP9 | |
| SCHEMBL30341837 | 0.73 | KLK7 (0.54) | SIRT2CTSLITGB3 | |
| SCHEMBL30685134 | 0.73 | DPP8 (0.69) | DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353833-A1 | DPP9 BINDING COMPOUNDS | UNIV ANTWERPEN (BE) | 2025-11-20 | — | — | US | disclosed |
| WO-2023233024-A1 | DPP9 BINDING COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2023-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353833-A1 | DPP9 BINDING COMPOUNDS | DPP9, DPP7, DPP3 | SIRT2 3391/4885CTSL 207/4885FOLH1 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.