Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.42 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.42 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.42 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20867336 | 0.88 | HDAC1 (0.36) | LMNAPOLB | |
| SCHEMBL23871973 | 0.87 | TP53 (0.43) | LMNAPOLBRAB9ACA1CA2 | |
| SCHEMBL10180988 | 0.85 | CNR1 (0.55) | POLBFAAHPSMB11PSMA7PSMB1 | |
| SCHEMBL20861736 | 0.82 | HDAC1 (0.35) | — | |
| SCHEMBL12726010 | 0.79 | DEGS1 (0.51) | CETPHSP90AA1SOAT1LMNADEGS1 | |
| SCHEMBL22019074 | 0.75 | NPC1 (0.38) | LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL25827826 | 0.74 | TRPV1 (0.49) | FAAH | |
| SCHEMBL774744 | 0.74 | SOAT1 (0.44) | CETPHSP90AA1SOAT1LMNADEGS1 | |
| SCHEMBL775687 | 0.74 | SOAT1 (0.44) | CETPHSP90AA1SOAT1LMNADEGS1 | |
| SCHEMBL10336422 | 0.73 | CETP (0.39) | CETPHSP90AA1SOAT1LMNADEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023242278-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KIDNEY DISEASES | UNIVERSITÄTSMEDIZIN GREIFSWALD (DE) | 2023-12-21 | — | — | WO | disclosed |