Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.37 |
| ▸ | ABAT | P80404 | 3/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769958 | 0.84 | ALDH1A3 (0.43) | ALDH1A3ALDH1A1ALDH3A1RAB9AKDM4E | |
| SCHEMBL30021376 | 0.82 | ALDH1A3 (0.49) | ALDH1A3ALDH1A1ALDH3A1RAB9AKDM4E | |
| SCHEMBL14329287 | 0.82 | ALDH1A3 (0.49) | ALDH1A3ALDH1A1ALDH3A1RAB9AKDM4E | |
| SCHEMBL2909366 | 0.82 | ALDH1A3 (0.58) | ALDH1A3ALDH1A1ALDH3A1RAB9AKDM4E | |
| SCHEMBL2601956 | 0.81 | KDM4E (0.46) | ALDH1A1RAB9AKDM4EPTGS2NPC1 | |
| SCHEMBL22490053 | 0.80 | ALDH1A3 (0.47) | ALDH1A3ALDH1A1ALDH3A1RAB9AKDM4E | |
| SCHEMBL28829387 | 0.78 | ALDH1A3 (0.46) | ALDH1A3ALDH1A1ALDH3A1RAB9AKDM4E | |
| SCHEMBL5521189 | 0.78 | KDM4E (0.59) | ALDH1A1RAB9AKDM4EPTGS2TDP1 | |
| SCHEMBL11013337 | 0.77 | ALDH1A3 (0.45) | ALDH1A3ALDH1A1ALDH3A1RAB9AKDM4E | |
| SCHEMBL14709469 | 0.76 | ALDH1A1 (0.43) | ALDH1A3ALDH1A1ALDH3A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252679-A1 | A NEW TYPE OF BENZOXABOROLE-BASED ANTI-PNEUMOCOCCAL COMPOUNDS TARGETING LEUCYL-TRNA SYNTHETASE | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020252679-A1 | A NEW TYPE OF BENZOXABOROLE-BASED ANTI-PNEUMOCOCCAL COMPOUNDS TARGETING LEUCYL-TRNA SYNTHETASE | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2020-12-24 | — | — | WO | disclosed |
| US-8088768-B2 | Protein kinase and phosphatase inhibitors | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 2012-01-03 | — | — | US | disclosed |
| US-20110136807-A1 | Bicyclic compositions and methods for modulating a kinase cascade | KINEX PHARMACEUTICALS, LLC (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110028474-A1 | PROTEIN KINASE AND PHOSPHATASE INHIBITORS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028474-A1 | PROTEIN KINASE AND PHOSPHATASE INHIBITORS | PTPN5, PTPN2, PTPN4 | ALDH1A3 4401/4885ALDH1A1 4474/4885ALDH3A1 3884/4885 |
| US-20110136807-A1 | Bicyclic compositions and methods for modulating a kinase cascade | MAP3K20, MAP3K6, MAP3K2 | ALDH1A3 4592/4885ALDH1A1 4720/4885ALDH3A1 4024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.