Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.44 |
| ▸ | ABAT | P80404 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30225085 | 0.83 | KDM4E (0.59) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL4371754 | 0.83 | KDM4E (0.59) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL3431177 | 0.83 | KDM4E (0.59) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL2601956 | 0.83 | KDM4E (0.46) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL29951708 | 0.82 | KDM4E (0.57) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL27453852 | 0.82 | ALDH1A1 (0.43) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL8799179 | 0.80 | KDM4E (0.55) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL17058725 | 0.80 | KDM4E (0.50) | KDM4EPTGS2RAB9AALDH1A1AOX1 | |
| SCHEMBL27837492 | 0.79 | TRPA1 (0.44) | KDM4EPTGS2RAB9AALDH1A1TDP1 | |
| SCHEMBL7251582 | 0.79 | KDM4E (0.53) | KDM4EPTGS2RAB9AALDH1A1AOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024521-B2 | Isoquinoline derivatives, methods of synthesis and uses thereof | PROSETTA BIOSCIENCES, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-9512063-B2 | Process for the preparation of advantame | DIVI'S LABORATORIES LIMITED (IN) | 2016-12-06 | — | — | US | disclosed |
| US-20160304439-A1 | PROCESS FOR THE PREPARATION OF ADVANTAME | DIVI'S LABORATORIES LIMITED (IN) | 2016-10-20 | — | — | US | disclosed |
| US-20160194274-A1 | PHENANTHRENE DERIVATIVES FOR USE AS MEDICAMENTS | VALENTIA BIOPHARMA (ES) | 2016-07-07 | — | — | US | disclosed |
| US-9085559-B2 | Triazine-aryl-bis-indoles and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-07-21 | — | — | US | disclosed |
| US-20120283263-A1 | TRIAZINE-ARYL-BIS-INDOLES AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-11-08 | — | — | US | disclosed |
| US-20100087475-A1 | PHARMACEUTICAL COMPOUNDS | Biovali Laboratories International (Barbados) S.R.L. (BB) | 2010-04-08 | — | — | US | disclosed |
| WO-2010026436-A2 | PHARMACEUTICAL COMPOUNDS | BIOVAIL LABORATORIES INTERNATIONAL (BARBADOS) SRL (BB) | 2010-03-11 | — | — | WO | disclosed |
| US-7205425-B2 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | CHISSO CORPORATION (JP) | 2007-04-17 | — | — | US | disclosed |
| US-20070060656-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | SHIBASAKI MASAKATSU | 2007-03-15 | — | — | US | disclosed |
| US-20070032479-A1 | Treatment of inflammatory disorders of the epithelium with low dose 2,3-benzodiazepines | VELA ACQUISITION CORPORATION | 2007-02-08 | — | — | US | disclosed |
| US-20050148801-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | JNC CORPORATION (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-0947498-B1 | OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVES, AND PROCESS FOR PREPARING THE SAME | CHISSO CORP (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6632955-B1 | Optically active 1-substituted phenyl-2-nitro alcohol derivatives which are useful pharmaceutical intermediates. Enantiomotphs active 1-substituted phenyl-2-nitro alcohol derivatives. From these nitro alcohol such as albutramin and | CHISSO CORPORATION (JP) | 2003-10-14 | — | — | US | disclosed |
| US-20020193447-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | JNC CORPORATION (JP) | 2002-12-19 | — | — | US | disclosed |
| EP-0947498-A1 | OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATES, AND PROCESS FOR PREPARING THE SAME | CHISSO CORPORATION (JP) | 1999-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148801-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | ADH1A, ALDH7A1, ADRB1 | KDM4E 3275/4885PTGS2 1535/4885RAB9A 951/4885 |
| US-20120283263-A1 | TRIAZINE-ARYL-BIS-INDOLES AND PROCESS FOR PREPARATION THEREOF | AHR, IDO2, IDO1 | KDM4E 910/4885PTGS2 184/4885RAB9A 3417/4885 |
| US-12024521-B2 | Isoquinoline derivatives, methods of synthesis and uses thereof | POLRMT, MAVS, SYNCRIP | KDM4E 2540/4885PTGS2 1407/4885RAB9A 1825/4885 |
| US-20160304439-A1 | PROCESS FOR THE PREPARATION OF ADVANTAME | TASP1, ASPH, COMT | KDM4E 563/4885PTGS2 4547/4885RAB9A 4815/4885 |
| US-20070032479-A1 | Treatment of inflammatory disorders of the epithelium with low dose 2,3-benzodiazepines | GABBR2, GABBR1, GABRB3 | KDM4E 4050/4885PTGS2 301/4885RAB9A 2984/4885 |
| US-20070060656-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | ADH1A, ALDH7A1, ADRB1 | KDM4E 3275/4885PTGS2 1535/4885RAB9A 951/4885 |
| US-20020193447-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | ADH1A, ALDH7A1, SARM1 | KDM4E 3071/4885PTGS2 1490/4885RAB9A 1036/4885 |
| US-20100087475-A1 | PHARMACEUTICAL COMPOUNDS | UGT2B7, CYP3A7, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | KDM4E 1817/4885PTGS2 1125/4885RAB9A 319/4885 |
| US-20160194274-A1 | PHENANTHRENE DERIVATIVES FOR USE AS MEDICAMENTS | HTT, TARDBP, ATXN2 | KDM4E 1260/4885PTGS2 3146/4885RAB9A 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.