Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531723 | 0.87 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14345594 | 0.87 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13815587 | 0.86 | THRB (0.36) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL22657385 | 0.85 | THRB (0.40) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16309307 | 0.85 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9795107 | 0.85 | CA2 (0.40) | TSHRALDH1A1TDP1CA2MEN1 | |
| SCHEMBL15237111 | 0.84 | THRB (0.44) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4917590 | 0.84 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11964784 | 0.84 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8430137 | 0.84 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024116106-A1 | OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF | Johnson & Johnson Surgical Vision, Inc. (US) | 2024-06-06 | — | — | WO | disclosed |