SCHEMBL22657385

SCHEMBL22657385

C=C(C)C(=O)OCCNC(=O)NNC(=O)CN

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.39
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23943679 0.86 THRB (0.43) THRBTSHRPOLBAPEX1HTT
SCHEMBL27360180 0.85 THRB (0.46) THRBTSHRPOLBAPEX1HTT
SCHEMBL23943743 0.84 THRB (0.42) THRBTSHRPOLBAPEX1HTT
SCHEMBL23943455 0.84 THRB (0.44) THRBTSHRPOLBAPEX1HTT
SCHEMBL23943892 0.83 THRB (0.47) THRBTSHRPOLBAPEX1HTT
SCHEMBL23943854 0.82 THRB (0.40) THRBTSHRPOLBAPEX1HTT
SCHEMBL2195083 0.82 THRB (0.52) THRBTSHRPOLBAPEX1HTT
SCHEMBL23943901 0.81 THRB (0.42) THRBTSHRPOLBAPEX1HTT
SCHEMBL17124679 0.81 THRB (0.44) THRBTSHRPOLBAPEX1HTT
SCHEMBL29498100 0.78 THRB (0.39) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4506373-A2 POLYMER WITH UPPER CRITICAL SOLUTION TEMPERATURE IN AQUEOUS SOLUTION The Boeing Company (US) 2025-02-12 EP disclosed
EP-3969489-B1 POLYMER WITH UPPER CRITICAL SOLUTION TEMPERATURE IN AQUEOUS SOLUTION BOEING CO (US) 2024-12-25 EP disclosed
US-20230286911-A1 POLYMER WITH UPPER CRITICAL SOLUTION TEMPERATURE THE BOEING COMPANY 2023-09-14 US disclosed
US-11673858-B2 Polymer with upper critical solution temperature THE BOEING COMPANY (US) 2023-06-13 US disclosed
EP-3969489-A1 POLYMER WITH UPPER CRITICAL SOLUTION TEMPERATURE IN AQUEOUS SOLUTION The Boeing Company (US) 2022-03-23 EP disclosed
US-20200361859-A1 Polymer with upper critical solution temperature THE UNIVERSITY OF QUEENSLAND (AU) 2020-11-19 US disclosed
WO-2020231703-A1 POLYMER WITH UPPER CRITICAL SOLUTION TEMPERATURE IN AQUEOUS SOLUTION THE BOEING COMPANY (US) 2020-11-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361859-A1 Polymer with upper critical solution temperature MPST, ULK2, ULK3 THRB 1541/4885TSHR 2309/4885POLB 3752/4885
US-11673858-B2 Polymer with upper critical solution temperature MPST, ULK2, ULK3 THRB 1541/4885TSHR 2309/4885POLB 3752/4885
US-20230286911-A1 POLYMER WITH UPPER CRITICAL SOLUTION TEMPERATURE MPST, ULK2, ULK3 THRB 1541/4885TSHR 2309/4885POLB 3752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.