SCHEMBL27360289

SCHEMBL27360289

CC(=C(Cl)c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
HIF1A Q16665 1/20 0.48
ESR1 P03372 2/20 0.46
DAO P14920 1/20 0.43
TSHR P16473 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
CES2 O00748 4/20 0.42
CES1 P23141 4/20 0.42
PTGS2 P35354 2/20 0.39
SRD5A2 P31213 1/20 0.37
KDM1A O60341 1/20 0.36
CYP19A1 P11511 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9551210 0.87 CYP19A1 (0.52) ALDH1A1HIF1AESR1TSHRPTGS2
SCHEMBL11063680 0.81 ALDH1A1 (0.50) ALDH1A1HIF1AESR1DAOTSHR
SCHEMBL11063679 0.81 ALDH1A1 (0.50) ALDH1A1HIF1AESR1DAOTSHR
SCHEMBL7914830 0.81 ALDH1A1 (0.50) ALDH1A1HIF1AESR1DAOTSHR
SCHEMBL16934008 0.81 ALDH1A1 (0.50) ALDH1A1HIF1AESR1DAOTSHR
SCHEMBL9824912 0.81 ESR1 (0.48) ALDH1A1HIF1AESR1DAOTSHR
SCHEMBL3940726 0.80 TSHR (0.56) ALDH1A1HIF1AESR1DAOTSHR
SCHEMBL3940728 0.80 TSHR (0.56) ALDH1A1HIF1AESR1DAOTSHR
SCHEMBL11844374 0.80 ESR1 (0.56) ALDH1A1ESR1DAOTSHRNAPRT
SCHEMBL1035354 0.80 ESR1 (0.56) ALDH1A1ESR1DAOTSHRNAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1055771-C Organic photoconductive drum for laser printer and method for manufacturing the same CHINESE ACAD INST CHEMISTRY (CN) 2000-08-23 CN disclosed
CN-1144343-A Organic photoconductive drum for laser printer and method for manufacturing the same CHINESE ACAD INST CHEMISTRY (CN) 1997-03-05 CN disclosed