Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063679 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HIF1AESR1TSHRDAO | |
| SCHEMBL11063680 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HIF1AESR1TSHRDAO | |
| SCHEMBL16934008 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HIF1AESR1TSHRDAO | |
| SCHEMBL3940726 | 0.82 | TSHR (0.56) | ALDH1A1HIF1AESR1TSHRDAO | |
| SCHEMBL3940728 | 0.82 | TSHR (0.56) | ALDH1A1HIF1AESR1TSHRDAO | |
| SCHEMBL27360289 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HIF1AESR1TSHRDAO | |
| SCHEMBL28858497 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HIF1AESR1TSHRDAO | |
| SCHEMBL28858494 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HIF1AESR1TSHRDAO | |
| SCHEMBL59763 | 0.77 | TSHR (0.50) | ALDH1A1HIF1AESR1TSHRDAO | |
| SCHEMBL7875628 | 0.77 | TSHR (0.50) | ALDH1A1HIF1AESR1TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255424-B1 | COUPLING POLYMERIC PRECURSOR SEGMENTS, EACH HAVING LIVING END CAPABLE OF REACTING IN POLYMERIZATION REACTION, TOGETHER IN CONVERGENT MANNER INVOLVING REACTION OF MULTIFUNCTIONAL COUPLING AGENT TO FORM HYPERBRANCHED STRUCTURE | COLORADO SCHOOL OF MINES | 2001-07-03 | — | — | US | disclosed |
| US-5326489-A | Sulfonated polymer | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0523300-B1 | Electrorheological fluids | NIPPON CATALYTIC CHEM IND (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0523300-A1 | Electrorheological fluids | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0108627-A2 | Cephalosporin derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-16 | — | — | EP | disclosed |
| US-3969433-A | ADDITION POLYMER | KOSE AKIRA | 1976-07-13 | — | — | US | disclosed |