Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902058 | 0.82 | ESR1 (0.56) | ESR1CES2CES1PTGS2ALDH1A1 | |
| SCHEMBL11844374 | 0.82 | ESR1 (0.56) | ESR1CES2CES1PTGS2ALDH1A1 | |
| SCHEMBL1035354 | 0.82 | ESR1 (0.56) | ESR1CES2CES1PTGS2ALDH1A1 | |
| SCHEMBL27360289 | 0.81 | ALDH1A1 (0.48) | ESR1CES2CES1PTGS2ALDH1A1 | |
| SCHEMBL23278527 | 0.79 | ESR1 (0.61) | ESR1CES2CES1PTGS2ALDH1A1 | |
| SCHEMBL5209642 | 0.79 | ESR1 (0.45) | ESR1CES2CES1PTGS2ALDH1A1 | |
| SCHEMBL23374547 | 0.79 | ESR1 (0.45) | ESR1CES2CES1PTGS2ALDH1A1 | |
| SCHEMBL8676275 | 0.77 | ESR1 (0.58) | ESR1CES2CES1PTGS2ALDH1A1 | |
| SCHEMBL58000 | 0.77 | ESR1 (0.52) | ESR1CES2CES1PTGS2ALDH1A1 | |
| SCHEMBL2465558 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527593-B1 | ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER | ASAHI CHEMICAL IND (JP) | 2025-07-23 | — | — | EP | disclosed |
| EP-3527600-B1 | ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER | ASAHI CHEMICAL IND (JP) | 2025-07-09 | — | — | EP | disclosed |
| CN-112979917-B | Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer | 旭化成株式会社 | 2023-04-25 | — | — | CN | disclosed |
| US-20230114799-A1 | ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-04-13 | — | — | US | disclosed |
| US-11548975-B2 | Isocyanate composition and method for producing isocyanate polymer | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-01-10 | — | — | US | disclosed |
| CN-109790269-B | Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer | 旭化成株式会社 | 2022-06-14 | — | — | CN | disclosed |
| CN-109803992-B | Isocyanate composition and method for producing isocyanate polymer | 旭化成株式会社 | 2022-05-24 | — | — | CN | disclosed |
| EP-3536683-B1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | ASAHI CHEMICAL IND (JP) | 2021-11-24 | — | — | EP | disclosed |
| CN-107963982-B | Polyisocyanate composition and isocyanate polymer composition | 旭化成株式会社 | 2021-11-12 | — | — | CN | disclosed |
| US-11118001-B2 | Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-09-14 | — | — | US | disclosed |
| US-20150210631-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-07-30 | — | — | US | disclosed |
| EP-0032062-B2 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0270709-B1 | PROCESS FOR THE PRODUCTION OF VINYL POLYMERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-02-06 | — | — | EP | disclosed |
| EP-0270709-A1 | Process for the production of vinyl polymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-15 | — | — | EP | disclosed |
| EP-0032062-B1 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
| US-4345054-A | High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| EP-0032062-A2 | High-molecular-weight novolak substituted phenolic resins and their preparation | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-15 | — | — | EP | disclosed |
| EP-0009361-A1 | 2-Alkoxycarbonylamino benzimidazoles having a halogen-containing substituent, their preparation and their use as parasiticides | MERCK & CO. INC. (US) | 1980-04-02 | — | — | EP | disclosed |
| US-4174400-A | Anthelmintic benzimidazoles | MERCK & CO., INC. (US) | 1979-11-13 | — | — | US | disclosed |
| US-4064239-A | LIVER FLUKES | MERCK & CO., INC. (US) | 1977-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548975-B2 | Isocyanate composition and method for producing isocyanate polymer | IDH3A, IDH2, IDH3B | ESR1 3542/4885CES2 974/4885CES1 2463/4885 |
| US-20230114799-A1 | ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER | IDH3A, IDH2, IDH3B | ESR1 3404/4885CES2 959/4885CES1 2329/4885 |
| US-11118001-B2 | Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer | IDH3A, IPO4, IDH3B | ESR1 4660/4885CES2 1939/4885CES1 3404/4885 |
| US-20150210631-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | TST, SUDS3, SCLY | ESR1 2237/4885CES2 612/4885CES1 1847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.