Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28194680 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRLTA4HCYP3A4 | |
| SCHEMBL27383200 | 0.90 | PPARG (0.42) | ALDH1A1LMNATSHRLTA4HCYP3A4 | |
| SCHEMBL27362587 | 0.90 | NR5A1 (0.51) | ALDH1A1LMNATSHRLTA4HCYP3A4 | |
| SCHEMBL27382619 | 0.87 | HTR2A (0.39) | ALDH1A1LMNATSHRLTA4HCYP3A4 | |
| SCHEMBL27381822 | 0.86 | TSHR (0.41) | ALDH1A1LMNATSHRLTA4HCYP3A4 | |
| SCHEMBL27362584 | 0.86 | TP53 (0.57) | TSHRTP53NPC1RAB9AMAPT | |
| SCHEMBL27852637 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRLTA4HCYP3A4 | |
| SCHEMBL7114372 | 0.85 | NPC1 (0.40) | ALDH1A1LMNATSHRLTA4HCYP3A4 | |
| SCHEMBL28337807 | 0.85 | LTA4H (0.46) | ALDH1A1LMNATSHRLTA4HCYP3A4 | |
| SCHEMBL27616820 | 0.85 | LTA4H (0.46) | ALDH1A1LMNATSHRLTA4HCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102816082-B | Benzamide derivant and preparation method and application thereof | UNIV ZHEJIANG | 2015-03-11 | — | — | CN | disclosed |
| CN-101817761-B | Benzoate derivative, preparation method and application | UNIV ZHEJIANG | 2014-06-25 | — | — | CN | disclosed |
| CN-102816082-A | Benzamide derivant and preparation method and application thereof | UNIV ZHEJIANG | 2012-12-12 | — | — | CN | disclosed |
| CN-102030877-B | Narrow-bandgap polypyrrylarylenemethine photoelectric functional polymer material and preparation method thereof | UNIV FUZHOU | 2012-06-06 | — | — | CN | disclosed |
| CN-102030877-A | Narrow-bandgap polypyrrylarylenemethine photoelectric functional polymer material and preparation method thereof | UNIV FUZHOU | 2011-04-27 | — | — | CN | disclosed |
| CN-101817761-A | Benzoate derivative, preparation method and application | UNIV ZHEJIANG | 2010-09-01 | — | — | CN | disclosed |
| CN-1069025-A | The aryl of platelet activating factor, acid amides, imide and carbamate pyridine antagonists | AMERICAN CYANAMID CO (US) | 1993-02-17 | — | — | CN | disclosed |