SCHEMBL28337807

SCHEMBL28337807

CCCCCCCCON(OCCCCCCCC)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.46
TSHR P16473 4/20 0.43
LMNA P02545 3/20 0.43
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 1/20 0.41
JAK2 O60674 1/20 0.41
RAB9A P51151 1/20 0.41
PAX8 Q06710 1/20 0.41
CYP3A4 P08684 3/20 0.41
MAPK1 P28482 2/20 0.41
TP53 P04637 2/20 0.41
NR1I2 O75469 2/20 0.40
CHRM2 P08172 2/20 0.40
ADRA2A P08913 2/20 0.40
OPRK1 P41145 2/20 0.40
HTR2B P41595 2/20 0.40
SLC6A3 Q01959 2/20 0.40
KCNH2 Q12809 2/20 0.40
MLNR O43193 1/20 0.40
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27616820 1.00 LTA4H (0.46) LTA4HTSHRLMNAALDH1A1NPC1
SCHEMBL28751604 0.98 LTA4H (0.44) LTA4HTSHRLMNAALDH1A1NPC1
Propylamine SCHEMBL27621937 0.93 LTA4H (0.41) LTA4HTSHRLMNAALDH1A1NPC1
SCHEMBL5830750 0.92 LTA4H (0.47) LTA4HTSHRALDH1A1NPC1JAK2
SCHEMBL28194680 0.85 ALDH1A1 (0.47) LTA4HTSHRLMNAALDH1A1NPC1
SCHEMBL27361074 0.85 ALDH1A1 (0.47) LTA4HTSHRLMNAALDH1A1NPC1
SCHEMBL11575309 0.84 LMNA (0.39) LTA4HTSHRLMNAALDH1A1CYP3A4
SCHEMBL27598274 0.82 LTA4H (0.41) LTA4HTSHRLMNAALDH1A1NPC1
SCHEMBL27908836 0.81 TSHR (0.45) LTA4HTSHRLMNAALDH1A1NPC1
SCHEMBL28569832 0.81 LTA4H (0.43) LTA4HTSHRLMNAALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110573566-B High efficiency phosphorus stabilizers based on diphenylamine and heterocyclic diphenylamine derivatives 弗劳恩霍夫应用研究促进协会 2021-07-30 CN disclosed
CN-110573566-A High efficiency phosphorus stabilizers based on diphenylamine and heterocyclic diphenylamine derivatives 弗劳恩霍夫应用研究促进协会 2019-12-13 CN disclosed