Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 7/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361258 | 0.74 | PTPN7 (0.54) | NPC1RAB9AKDM4EGLASTS | |
| SCHEMBL24595692 | 0.70 | STS (0.48) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL24595695 | 0.68 | STS (0.48) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL15286102 | 0.68 | NPC1 (0.85) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18583499 | 0.67 | ACHE (0.46) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL13486911 | 0.67 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18558872 | 0.67 | NPC1 (0.70) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL27085590 | 0.67 | NPC1 (0.66) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL7116819 | 0.67 | NPC1 (0.83) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL9607852 | 0.67 | RAB9A (0.63) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235753-A2 | ALDH2 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-12-07 | — | — | WO | disclosed |