SCHEMBL27361302

SCHEMBL27361302

CC(N)([Si](c1ccccc1)(c1ccccc1)c1ccccc1)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.41
SLC6A2 P23975 1/20 0.41
KCNN4 O15554 1/20 0.38
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
AKT1 P31749 1/20 0.34
AKT2 P31751 1/20 0.34
MAPK1 P28482 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
CYP2C19 P33261 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 2/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3526796 0.78 ESR1 (0.37) TAAR1SLC6A2KCNN4ESR1ESR2
SCHEMBL31439754 0.74 NR1H2 (0.41) ESR1ESR2MAPK1MAPTKMT2A
SCHEMBL841941 0.72 TAAR1 (0.34) TAAR1SLC6A2KCNN4ESR1ESR2
SCHEMBL27719607 0.69 ESR1 (0.44) ESR1ESR2MAPK1MAPTKMT2A
SCHEMBL25490757 0.69 TSHR (0.43) ESR1ESR2MAPTKMT2ANR1H2
SCHEMBL9862813 0.69 ALDH1A1 (0.33) ESR1ESR2MAPK1MAPTCYP2C19
SCHEMBL9233389 0.69 MAPK1 (0.39) ESR1ESR2MAPK1ALDH1A1ALOX15
SCHEMBL113062 0.68 TAAR1 (0.36) TAAR1SLC6A2KCNN4ESR1ESR2
SCHEMBL25221066 0.67 ESR1 (0.30) ESR1ESR2
SCHEMBL29749402 0.67 ESR1 (0.37) TAAR1SLC6A2KCNN4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1055992-C A control apparatus and method for an air conditioner SAMSUNG ELECTRONICS CO LTD (KR) 2000-08-30 CN disclosed