SCHEMBL3526796

SCHEMBL3526796

CC(C)(C)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.37
ESR2 Q92731 3/20 0.37
MAPK1 P28482 1/20 0.36
NR1H2 P55055 2/20 0.34
NR1H3 Q13133 2/20 0.34
TAAR1 Q96RJ0 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
ALOX15 P16050 1/20 0.33
SLC6A2 P23975 1/20 0.33
ATM Q13315 1/20 0.32
CYP3A4 P08684 1/20 0.32
AOC3 Q16853 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM1 P11229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25490757 0.88 TSHR (0.43) ESR1ESR2NR1H2NR1H3ALDH1A1
SCHEMBL25221066 0.86 ESR1 (0.30) ESR1ESR2
SCHEMBL25490551 0.82 ACHE (0.42) MAPK1ALDH1A1LMNATSHRALOX12
SCHEMBL28214807 0.81 NR1H2 (0.30) NR1H2NR1H3
SCHEMBL27361302 0.78 TAAR1 (0.41) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL31439754 0.78 NR1H2 (0.41) ESR1ESR2MAPK1NR1H2NR1H3
SCHEMBL2542131 0.78 CYP2B6 (0.33) TSHR
SCHEMBL28429821 0.78 KDM4E (0.34) ALDH1A1LMNASLC6A2ATMCHRM2
SCHEMBL8789521 0.78 ALDH1A1 (0.39) ESR1ESR2NR1H2NR1H3ALDH1A1
SCHEMBL27562519 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807833-B2 Method for total synthesis of ecteinascidins and intermediate compounds thereof JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2010-10-05 US claimed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-11917900-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-11917900-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
WO-2024035123-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE 엘티소재주식회사 2024-02-15 WO disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-11832510-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-9627631-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-04-18 US disclosed
US-20160254463-A1 LAMINATE HAVING POROUS ORGANIC SEMICODUCTOR THIN FILM AND CHEMICAL SENSOR COMPRISING SAME CENTER FOR ADVANCED SOFT ELECTRONICS 2016-09-01 US disclosed
US-9318710-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-19 US disclosed
US-20160028016-A1 BORON-NITROGEN POLYAROMATIC COMPOUNDS AND THEIR USE IN OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-8999522-B2 6H-indolo[2,3-b]quinoxaline derivatives and organic light emitting diode using the same NATIONAL TSING HUA UNIVERSITY (TW) 2015-04-07 US disclosed
US-8999522-B2 6H-indolo[2,3-b]quinoxaline derivatives and organic light emitting diode using the same NATIONAL TSING HUA UNIVERSITY (TW) 2015-04-07 US disclosed
US-8680760-B2 Beta-diketone ancillary ligands and their metal complexes used in organic optoelectronic devices NATIONAL TSING HUA UNIVERSITY (TW) 2014-03-25 US disclosed
US-20140027734-A1 BORON-NITROGEN POLYAROMATIC COMPOUNDS AND THEIR USE IN OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2014-01-30 US disclosed
US-20110303901-A1 6H-INDOLO[2,3-b]QUINOXALINE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2011-12-15 US disclosed
US-20100270915-A1 Beta-Diketone Ancillary Ligands and Their Metal Complexes Used in Organic Optoelectronic Devices NATIONAL TSING HUA UNIVERSITY (TW) 2010-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832510-B2 Organic electroluminescent materials and devices OSBP, OCIAD2, OCIAD1 ESR1 326/4885ESR2 229/4885MAPK1 4132/4885
US-20100270915-A1 Beta-Diketone Ancillary Ligands and Their Metal Complexes Used in Organic Optoelectronic Devices PBK, DEK, OSTC ESR1 2175/4885ESR2 871/4885MAPK1 1880/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND ESR1 66/4885ESR2 138/4885MAPK1 4828/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 ESR1 314/4885ESR2 220/4885MAPK1 1193/4885
US-20110303901-A1 6H-INDOLO[2,3-b]QUINOXALINE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME IDO1, IPO9, IDO2 ESR1 1871/4885ESR2 2374/4885MAPK1 3022/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG ESR1 65/4885ESR2 105/4885MAPK1 3298/4885
US-11917900-B2 Organic electroluminescent materials and devices OTC, OSBP, OCIAD2 ESR1 278/4885ESR2 497/4885MAPK1 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.