SCHEMBL31439754

SCHEMBL31439754

CC(O)([Si](c1ccccc1)(c1ccccc1)c1ccccc1)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 3/20 0.41
NR1H3 Q13133 3/20 0.41
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
ALDH1A1 P00352 4/20 0.36
ALOX15 P16050 1/20 0.36
CYP3A4 P08684 2/20 0.34
TSHR P16473 4/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
MAPK1 P28482 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C19 P33261 2/20 0.32
LMNA P02545 1/20 0.32
HIF1A Q16665 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3526796 0.78 ESR1 (0.37) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL27361302 0.74 TAAR1 (0.41) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL9891044 0.70 ALDH1A1 (0.48) ESR1ESR2ALDH1A1ALOX15CYP3A4
SCHEMBL8789521 0.69 ALDH1A1 (0.39) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL25490757 0.69 TSHR (0.43) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL9233389 0.69 MAPK1 (0.39) ESR1ESR2ALDH1A1ALOX15TSHR
SCHEMBL9862813 0.69 ALDH1A1 (0.33) ESR1ESR2ALDH1A1CYP3A4TSHR
SCHEMBL564255 0.68 NR1H2 (0.39) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL272814 0.68 NR1H2 (0.39) NR1H2NR1H3ESR1ESR2ALDH1A1
SCHEMBL152027 0.68 NR1H2 (0.39) NR1H2NR1H3ESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 WO claimed
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 WO disclosed