Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCND2 | P30279 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31637504 | 0.80 | KMT2A (0.40) | FGFR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL27362189 | 0.80 | KMT2A (0.40) | FGFR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL25123264 | 0.78 | CCNE1 (0.36) | CDK4CCND1CCND3 | |
| SCHEMBL29991028 | 0.78 | CCNE1 (0.36) | CDK4CCND1CCND3 | |
| SCHEMBL29991131 | 0.77 | CYP1A2 (0.37) | FGFR1GRM4PIK3CA | |
| SCHEMBL27361790 | 0.72 | PSEN1 (0.45) | FGFR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL27229130 | 0.72 | BTK (0.37) | FGFR1SRCGRM4 | |
| SCHEMBL27361409 | 0.71 | CCND1 (0.54) | FGFR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL27166404 | 0.71 | WEE1 (0.47) | FGFR1CDK4CCND1CCND2CCND3 | |
| SCHEMBL29991471 | 0.70 | MAPK8 (0.68) | FGFR1CDK4CCND1CCND3MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039903-A2 | CDK2 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |