Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27359800 | 0.86 | MEN1 (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27363564 | 0.86 | ALDH1A1 (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL27360419 | 0.84 | LMNA (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL27380600 | 0.83 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL27359801 | 0.83 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27379175 | 0.81 | SMN1; SMN2 (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27528686 | 0.81 | MAPT (0.40) | RAB9ANPC1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL27363569 | 0.80 | LMNA (0.36) | RAB9AALDH1A1HPGDLMNACYP1A2 | |
| SCHEMBL27400434 | 0.79 | KDM4E (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27379146 | 0.78 | LMNA (0.44) | RAB9ANPC1SMN1; SMN2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1069882-A | The Compounds and methods for that suppresses HIV and correlated virus | MEDIVIR AB (CH) | 1993-03-17 | — | — | CN | disclosed |