Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975713 | 0.81 | ALDH1A1 (0.56) | OPRM1OPRK1DRD3ALDH1A1HTR2B | |
| SCHEMBL15610701 | 0.81 | ALDH1A1 (0.59) | OPRM1OPRK1DRD3ALDH1A1HTR2B | |
| SCHEMBL27362545 | 0.80 | MEN1 (0.62) | MEN1KMT2AOPRM1OPRK1OPRD1 | |
| SCHEMBL10754509 | 0.79 | ALDH1A1 (0.67) | MEN1KMT2AOPRM1OPRK1DRD3 | |
| SCHEMBL27355687 | 0.78 | MEN1 (0.56) | MEN1KMT2AOPRM1OPRK1OPRD1 | |
| Hydrochloric Acid SCHEMBL11381615 | 0.78 | KDM4E (0.68) | MEN1KMT2AOPRM1OPRK1DRD3 | |
| SCHEMBL15610663 | 0.77 | LMNA (0.58) | OPRM1OPRK1DRD3ALDH1A1HTR2B | |
| SCHEMBL28688629 | 0.76 | MEN1 (1.00) | MEN1KMT2ADRD3ALDH1A1HTR2B | |
| SCHEMBL29373969 | 0.76 | MEN1 (1.00) | MEN1KMT2ADRD3ALDH1A1HTR2B | |
| SCHEMBL27528708 | 0.75 | MEN1 (0.53) | MEN1KMT2AOPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058709-C | Amide compounds for medical treatment | PFIZER (US) | 2000-11-22 | — | — | CN | disclosed |
| CN-1141918-A | Amide compounds for medical treatment | PFIZER (US) | 1997-02-05 | — | — | CN | disclosed |