Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27569191 | 0.83 | OPRM1 (0.85) | OPRM1OPRD1OPRK1 | |
| SCHEMBL27362549 | 0.82 | MEN1 (0.55) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6972464 | 0.82 | SIGMAR1 (0.52) | MEN1KMT2AACACBHPGDSIGMAR1 | |
| SCHEMBL27343001 | 0.81 | MEN1 (0.54) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL12607818 | 0.81 | TMEM97 (0.62) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL27361573 | 0.80 | MEN1 (0.60) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL14234933 | 0.80 | SIGMAR1 (0.64) | MEN1KMT2AHPGDCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL1785554 | 0.80 | TMEM97 (0.61) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL4239488 | 0.79 | MEN1 (0.61) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL3691859 | 0.79 | OPRM1 (0.85) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058709-C | Amide compounds for medical treatment | PFIZER (US) | 2000-11-22 | — | — | CN | disclosed |
| CN-1141918-A | Amide compounds for medical treatment | PFIZER (US) | 1997-02-05 | — | — | CN | disclosed |