Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27361883

COS(=O)(=O)c1ccccc1N.N

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
CA9 Q16790 4/20 0.54
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA12 O43570 2/20 0.54
CA4 P22748 2/20 0.54
CA5A P35218 2/20 0.54
CYP2C9 P11712 1/20 0.54
CA6 P23280 1/20 0.54
CA7 P43166 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
HTR6 P50406 2/20 0.48
ALDH1A1 P00352 2/20 0.40
ADRA2B P18089 1/20 0.40
PTGS1 P23219 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KYNU Q16719 2/20 0.39
CFTR P13569 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1459150 0.98 GAA (0.58) GAACA9CA1CA2CA12
SCHEMBL29415251 0.82 HTR6 (0.43) GAACA9CA1CA2CA12
SCHEMBL777664 0.82 HTR6 (0.43) GAACA9CA1CA2CA12
SCHEMBL7576202 0.80 GAA (0.62) GAACA9CA1CA2CA12
SCHEMBL15274084 0.79 TTR (0.59) GAACA2ALDH1A1TDP1HSD17B10
SCHEMBL7055443 0.78 GAA (0.60) GAACA9CA1CA2CA12
SCHEMBL8779870 0.78 GAA (0.54) GAACA9CA1CA2CA12
SCHEMBL1459622 0.77 JAK2 (0.40) GAACA9CA1CA2CA12
Methane SCHEMBL9696174 0.77 GAA (0.58) GAACA9CA1CA2CA12
SCHEMBL10818359 0.76 GAA (0.52) GAACA9CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1067419-C Reactive dyestuffs their preparation and their use BAYER AG (DE) 2001-06-20 CN disclosed
CN-1106845-A Reactive dyestuffs their preparation and their use BAYER AG (DE) 1995-08-16 CN disclosed