Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418440 | 0.74 | ADRA1A (0.36) | ADRA1A | |
| SCHEMBL26530978 | 0.73 | HTR2C (0.62) | HTR6OPRL1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL22156301 | 0.72 | PDE1A (0.41) | OPRL1SLC6A4SLC6A2CYP2D6SLC6A3 | |
| SCHEMBL21163634 | 0.71 | HTR2C (0.46) | HTR6HTR2C | |
| SCHEMBL22781622 | 0.70 | HTR2C (0.42) | OPRL1HTR2CPDE10A | |
| SCHEMBL9442675 | 0.69 | HTR6 (0.40) | HTR6OPRL1HTR2C | |
| SCHEMBL24749657 | 0.68 | OPRL1 (0.34) | HTR6OPRL1HTR2C | |
| SCHEMBL27603328 | 0.68 | ADRA1A (0.33) | ADRA1A | |
| SCHEMBL27362715 | 0.68 | PTGDR2 (0.42) | ADRA1A | |
| SCHEMBL27672685 | 0.67 | HTR2C (0.42) | HTR6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026484-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |