Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 13/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | VCP | P55072 | 2/20 | 0.38 |
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976223 | 0.91 | — | — | |
| SCHEMBL13497566 | 0.91 | — | — | |
| Benzene SCHEMBL28065160 | 0.71 | FBP1 (0.46) | FBP1HSP90AA1VCPTLR4TLR2 | |
| SCHEMBL2701677 | 0.69 | — | — | |
| SCHEMBL5957000 | 0.69 | — | — | |
| SCHEMBL28412355 | 0.66 | — | — | |
| Benzene SCHEMBL28841490 | 0.66 | ALDH1A1 (0.42) | FBP1MEN1ALDH1A1KMT2ALMNA | |
| Benzene SCHEMBL27534428 | 0.66 | ALDH1A1 (0.42) | FBP1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL9511629 | 0.65 | — | — | |
| Benzene SCHEMBL27433682 | 0.65 | FBP1 (0.40) | FBP1HSP90AA1TLR4TLR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102115446-B | Method for catalytically synthesizing chiral curcumin analogs | UNIV EAST CHINA SCIENCE & TECH | 2014-05-07 | — | — | CN | claimed |
| CN-1058707-C | Process for synthesis of d1-trans-4-phenyl-5-0-chlorobenzyl-pyrrolidone-2 | KUNMING PLANTS INST CHINA ACAD (CN) | 2000-11-22 | — | — | CN | claimed |
| CN-1191218-A | Process for synthesis of d1-trans-4-phenyl-5-0-chlorobenzyl-pyrrolidone-2 | KUNMING PLANTS INST CHINESE AC (CN) | 1998-08-26 | — | — | CN | claimed |
| CN-103877080-B | 4,5-bis-replaces-medicinal usage of 2-Pyrrolidone compound | Key Laboratory of natural product chemistry, Chinese Academy of Sciences, Guizhou Province (CN) | 2016-01-27 | — | — | CN | disclosed |
| CN-103877080-A | New use of 4, 5-disubstituted-2-pyrrolidone compound | KEY LAB OF CHEMISTRY NATURAL PRODUCTS OF GUIZHOU PROVINCE AND CHINESE ACADEMY | 2014-06-25 | — | — | CN | disclosed |
| CN-102115446-B | Method for catalytically synthesizing chiral curcumin analogs | UNIV EAST CHINA SCIENCE & TECH | 2014-05-07 | — | — | CN | disclosed |
| CN-102115446-A | Method for catalytically synthesizing chiral curcumin analogs | UNIV EAST CHINA SCIENCE & TECH | 2011-07-06 | — | — | CN | disclosed |
| CN-1058707-C | Process for synthesis of d1-trans-4-phenyl-5-0-chlorobenzyl-pyrrolidone-2 | KUNMING PLANTS INST CHINA ACAD (CN) | 2000-11-22 | — | — | CN | disclosed |
| CN-1191218-A | Process for synthesis of d1-trans-4-phenyl-5-0-chlorobenzyl-pyrrolidone-2 | KUNMING PLANTS INST CHINESE AC (CN) | 1998-08-26 | — | — | CN | disclosed |