⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13497566 | 1.00 | — | — | |
| Benzene SCHEMBL27362307 | 0.91 | FBP1 (0.46) | — | |
| SCHEMBL2701677 | 0.76 | — | — | |
| SCHEMBL5957000 | 0.76 | — | — | |
| SCHEMBL28412355 | 0.72 | — | — | |
| SCHEMBL9511629 | 0.71 | — | — | |
| SCHEMBL17574719 | 0.64 | — | — | |
| SCHEMBL406091 | 0.64 | — | — | |
| SCHEMBL176 | 0.64 | — | — | |
| SCHEMBL10348306 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382736-B | The synthetic method of the chloro- 2- nitroethylene of 1,1- bis- and Nitenpyram | 江苏克胜集团股份有限公司 | 2019-09-03 | — | — | CN | claimed |
| CN-108864001-A | A kind of new method synthesizing ranitidine | 郑州明泽医药科技有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108822025-A | A kind of preparation method of Nitenpyram | 上海晋景化学有限公司 | 2018-11-16 | — | — | CN | claimed |
| CN-107827822-A | A kind of method of one pot process 2 (Nitromethylene) imidazolidine | 上海生农生化制品股份有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-103524489-B | The synthesis technique of 2 chlorine 5 ((base of 2 (Nitromethylene) imidazolidine 1) methyl) pyridines | 华东理工大学 | 2018-02-09 | — | — | CN | claimed |
| CN-107382736-A | The synthetic method of the nitroethylene of 1,1 dichloro 2 and Nitenpyram | 江苏克胜集团股份有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-106892885-A | A kind of method for synthesizing ranitidine | 苏州弘森药业股份有限公司 | 2017-06-27 | — | — | CN | claimed |
| CN-105330593-A | Improved preparation method of nitenpyram | SHANGHAI JINJING CHEMICAL CO LTD | 2016-02-17 | — | — | CN | claimed |
| CN-103524489-A | Synthesis process of 2-chlorin-5-((2-(nitryl methylene) imidazoline-1-yl) methyl) pyridine | UNIV EAST CHINA SCIENCE & TECH | 2014-01-22 | — | — | CN | claimed |
| CN-101778823-B | Method for separating and purifying alpha-unsaturated amine compound | SUMITOMO CO LTD | 2013-02-13 | — | — | CN | claimed |
| CN-107382736-B | The synthetic method of the chloro- 2- nitroethylene of 1,1- bis- and Nitenpyram | 江苏克胜集团股份有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-107382736-B | The synthetic method of the chloro- 2- nitroethylene of 1,1- bis- and Nitenpyram | 江苏克胜集团股份有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-107382736-B | The synthetic method of the chloro- 2- nitroethylene of 1,1- bis- and Nitenpyram | 江苏克胜集团股份有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-108864001-A | A kind of new method synthesizing ranitidine | 郑州明泽医药科技有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108864001-A | A kind of new method synthesizing ranitidine | 郑州明泽医药科技有限公司 | 2018-11-23 | — | — | CN | disclosed |
| US-4175209-A | Preparation of 6,11-dihydro-11-oxodibenz[b,e]-oxepin-2-acetic acid and precursors therefor | AMERICAN HOECHST CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |
| US-4160781-A | 4-Benzyloxy-3-(chlorocarbonyl)-phenylacetyl chloride | AMERICAN HOECHST CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4153790-A | 4-Benzyloxy-3-(benzyloxy carbonyl)phenylthioacetmorpholide | AMERICAN HOECHST CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4153791-A | 3-Carboxy-4 hydroxyphenylthioacetmorpholide | AMERICAN HOECHST CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4118401-A | Preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid and precursors therefor | AMERICAN HOECHST CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |