Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362244 | 0.83 | CYP2A6 (0.54) | RAB9AMEN1KMT2APDE10ANPC1 | |
| SCHEMBL13831044 | 0.82 | MEN1 (0.54) | RAB9AMEN1KMT2ATRPV3ASIC3 | |
| SCHEMBL4263972 | 0.81 | KCNH2 (0.48) | KCNH2CYP1A2 | |
| SCHEMBL27395036 | 0.81 | DGAT1 (0.43) | TRPV3ALDH1A1HCRTR1HCRTR2MAPT | |
| SCHEMBL13283433 | 0.80 | RAB9A (0.60) | RAB9AMEN1KMT2ATRPV3ASIC3 | |
| SCHEMBL12197594 | 0.79 | IDO1 (0.36) | RAB9AMEN1KMT2AKCNH2NPC1 | |
| SCHEMBL13831225 | 0.77 | KCNH2 (0.72) | RAB9AMEN1KMT2AASIC3KCNH2 | |
| SCHEMBL12576617 | 0.77 | RAB9A (0.56) | RAB9AMEN1KMT2ATRPV3ASIC3 | |
| SCHEMBL31705085 | 0.77 | RAB9A (0.56) | RAB9AMEN1KMT2ATRPV3ASIC3 | |
| SCHEMBL12223356 | 0.76 | KDM4E (0.44) | RAB9AMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |