SCHEMBL4263972

SCHEMBL4263972

CCOCc1cccc(COCC)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.48
P2RX7 Q99572 1/20 0.39
LMNA P02545 1/20 0.38
CXCR4 P61073 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
CYP1A2 P05177 1/20 0.36
PGK1 P00558 1/20 0.35
PGK2 P07205 1/20 0.35
HRH4 Q9H3N8 1/20 0.34
NCF1 P14598 1/20 0.34
GRIN2D O15399 2/20 0.33
GRIN3B O60391 2/20 0.33
GRIN1 Q05586 2/20 0.33
GRIN2A Q12879 2/20 0.33
GRIN2B Q13224 2/20 0.33
GRIN2C Q14957 2/20 0.33
GRIN3A Q8TCU5 2/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15477559 0.87 CCR1 (0.41) KCNH2CYP1A2NOS2
SCHEMBL15477558 0.86 KCNH2 (0.37) KCNH2P2RX7LMNACYP1A2NCF1
SCHEMBL27362339 0.81 RAB9A (0.50) KCNH2CYP1A2
SCHEMBL12197594 0.77 IDO1 (0.36) KCNH2
SCHEMBL16259461 0.76 TSHR (0.46) KCNH2HRH4NCF1
SCHEMBL7661242 0.76 KCNH2 (0.44) KCNH2LMNANPSR1PGK1PGK2
SCHEMBL3432856 0.76 SYK (0.46) LMNA
SCHEMBL4268808 0.76 CYSLTR1 (0.59) CYP1A2
SCHEMBL4276755 0.75 KCNH2 (0.52) KCNH2LMNANPSR1PGK1PGK2
SCHEMBL4272920 0.75 P2RX7 (0.44) P2RX7DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed
US-7422837-B2 Photosensitive composition FUJIFILM CORPORATION (JP) 2008-09-09 US disclosed
US-7422837-B2 Photosensitive composition FUJIFILM CORPORATION (JP) 2008-09-09 US disclosed