Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14553997 | 0.82 | SIGMAR1 (0.40) | SIGMAR1KCNH2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL27669152 | 0.81 | ALDH1A1 (0.38) | SIGMAR1HDAC1HDAC6ALDH1A1SMN1; SMN2 | |
| SCHEMBL20244826 | 0.80 | SIGMAR1 (0.42) | SIGMAR1KCNH2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL18290465 | 0.79 | SIGMAR1 (0.38) | SIGMAR1KCNH2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL24958729 | 0.77 | HDAC1 (0.41) | SIGMAR1KCNH2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL17493993 | 0.75 | KCNH2 (0.40) | SIGMAR1KCNH2HDAC1HDAC6 | |
| SCHEMBL31389736 | 0.75 | SIGMAR1 (0.43) | SIGMAR1KCNH2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL14552452 | 0.74 | KCNH2 (0.38) | SIGMAR1KCNH2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL15120059 | 0.74 | SIGMAR1 (0.37) | SIGMAR1KCNH2HDAC1HDAC6 | |
| SCHEMBL12064537 | 0.74 | SIGMAR1 (0.44) | SIGMAR1KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |