Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.40 |
| ▸ | CLK1 | P49759 | 4/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015693 | 0.85 | DYRK1A (0.49) | ALDH1A1HSD17B10DYRK1ACLK4CLK1 | |
| SCHEMBL18911978 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5RIPK1RIPK3 | |
| SCHEMBL7218395 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5RIPK1RIPK3 | |
| SCHEMBL1419323 | 0.81 | CYP2A6 (0.47) | ALDH1A1HSD17B10HSD11B1DYRK1ACLK4 | |
| SCHEMBL8039455 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10RIPK1RIPK3ESR1 | |
| SCHEMBL8039453 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10RIPK1RIPK3ESR1 | |
| SCHEMBL16693063 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HSD11B1DYRK1ACLK4 | |
| SCHEMBL1850868 | 0.75 | NFE2L2 (0.44) | ALDH1A1HSD17B10RIPK1RIPK3DYRK1A | |
| SCHEMBL1850866 | 0.75 | NFE2L2 (0.44) | ALDH1A1HSD17B10RIPK1RIPK3DYRK1A | |
| SCHEMBL584449 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TRPM5RIPK1RIPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622598-B | Aryl-pyrrolidine nitrile compounds and preparation method and purposes and agricultural insecticide and pest control method for desinsection | 河南好年景生物发展有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-104418800-A | Aryl pyridine/pyrimidine compound and application thereof | SINOCHEM CORP | 2015-03-18 | — | — | CN | claimed |
| CN-103124726-A | Pyrazole amide compound and use thereof | SINOCHEM CORP | 2013-05-29 | — | — | CN | claimed |
| CN-1072213-C | Process for the preparation of guanidine derivatives and intermediates thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-03 | — | — | CN | claimed |
| CN-110178851-A | A kind of Pesticidal combination of spirotetramat and Diacloden | 广西汇丰生物科技有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-109362774-A | Containing Diacloden and phoxim combined type granular insecticide | 吴继松 | 2019-02-22 | — | — | CN | disclosed |
| CN-104054739-B | Tebufenpyrad miticide composition | 上海生农生化制品股份有限公司 | 2018-04-27 | — | — | CN | disclosed |
| CN-107501256-A | A kind of preparation method of high-purity Diacloden | 北京怡力生物科技有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-105622598-B | Aryl-pyrrolidine nitrile compounds and preparation method and purposes and agricultural insecticide and pest control method for desinsection | 河南好年景生物发展有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-104447096-B | A kind of complex fertilizer and production method for preventing and treating fast-growing Eucalyptus Species looper | 广西乐土生物科技有限公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-104755476-B | Method for producing compound | 住友化学株式会社 | 2017-12-05 | — | — | CN | disclosed |
| CN-104054738-B | Etoxazole miticide composition | 上海生农生化制品有限公司 | 2017-09-29 | — | — | CN | disclosed |
| CN-107207438-A | Bipyridine compound is used for the purposes of harmful arthropod control with it | 住友化学株式会社 | 2017-09-26 | — | — | CN | disclosed |
| CN-104418800-B | Aryl pyrrole (phonetic) pyridine class compound and application thereof | 沈阳中化农药化工研发有限公司 | 2017-06-16 | — | — | CN | disclosed |
| CN-103124726-B | Pyrazol acid amide compounds and uses thereof | SINOCHEM CORP. (CN) | 2016-01-06 | — | — | CN | disclosed |
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-104418800-A | Aryl pyridine/pyrimidine compound and application thereof | SINOCHEM CORP | 2015-03-18 | — | — | CN | disclosed |
| CN-103124726-A | Pyrazole amide compound and use thereof | SINOCHEM CORP | 2013-05-29 | — | — | CN | disclosed |
| CN-102532162-A | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-1072213-C | Process for the preparation of guanidine derivatives and intermediates thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-03 | — | — | CN | disclosed |