SCHEMBL584449

SCHEMBL584449

Clc1ccc2scnc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
HSD11B1 P28845 1/20 0.50
HSD17B10 Q99714 1/20 0.50
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
TRPM5 Q9NZQ8 1/20 0.43
POLB P06746 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
IDO1 P14902 1/20 0.42
GLRA3 O75311 1/20 0.41
GLRB P48167 1/20 0.41
MAPK1 P28482 1/20 0.40
RIPK1 Q13546 1/20 0.40
RIPK3 Q9Y572 1/20 0.40
NR4A2 P43354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29354147 1.00 ALDH1A1 (0.50) ALDH1A1HSD11B1HSD17B10NPC1RAB9A
Ethane SCHEMBL27952962 0.96 HSD11B1 (0.48) ALDH1A1HSD11B1HSD17B10NPC1RAB9A
Hydrazine SCHEMBL27534771 0.96 HSD11B1 (0.48) ALDH1A1HSD11B1HSD17B10NPC1RAB9A
SCHEMBL8062628 0.92 NPC1 (0.49) ALDH1A1HSD11B1HSD17B10NPC1RAB9A
Benzo[D]Thiazole SCHEMBL9300997 0.91 ALDH1A1 (0.68) ALDH1A1HSD11B1HSD17B10NPC1RAB9A
SCHEMBL27843503 0.86 ALDH1A1 (0.43) ALDH1A1HSD11B1HSD17B10NPC1RAB9A
SCHEMBL27509201 0.85 ALDH1A1 (0.42) ALDH1A1HSD11B1HSD17B10NPC1RAB9A
SCHEMBL28258785 0.85 KDM4E (0.51) ALDH1A1HSD11B1HSD17B10NPC1RAB9A
SCHEMBL9146035 0.83 ALDH1A1 (0.44) ALDH1A1HSD11B1HSD17B10NPC1RAB9A
SCHEMBL593507 0.83 NPC1 (0.54) ALDH1A1HSD11B1HSD17B10NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004820-A CO utilization2Preparation of benzothiazoles method for preparing compounds 内蒙古工业大学 2025-05-16 CN claimed
CN-115433072-B Method for preparing aryl ketone by photocatalytic oxidation 浙江工业大学 2023-08-08 CN claimed
CN-115433072-A Method for preparing aryl ketone by photocatalytic oxidation 浙江工业大学 2022-12-06 CN claimed
CN-113045993-A Polishing solution for processing ultra-smooth low-damage bearing steel surface and application thereof 西南交通大学 2021-06-29 CN claimed
CN-109134173-B Simple method for synthesizing heterocyclic aryl ketone compound 河南师范大学 2021-03-16 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
CN-109134173-A The method of easy synthesizing heterocyclic aryl ketones compounds 河南师范大学 2019-01-04 CN claimed
EP-3004120-B1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION UNIV NANYANG TECH (SG) 2018-08-29 EP claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
US-20160136629-A1 SPIRO-1,1'-BINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALADIUM-CATALYZED ASYMMETRIC HECK REACTION NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-05-19 US claimed
EP-0368327-B1 Light-sensitive composition FUJI PHOTO FILM CO LTD (JP) 1995-02-15 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-5202221-A Photocrosslinkable copolymer having maleimido side chain, cyanine dye sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US claimed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-4102688-A CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY FUJI PHOTO FILM CO., LTD. (JP) 1978-07-25 US claimed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160136629-A1 SPIRO-1,1'-BINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALADIUM-CATALYZED ASYMMETRIC HECK REACTION SBK1, SIK1, PDPK1 ALDH1A1 576/4885HSD11B1 1254/4885HSD17B10 2066/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR ALDH1A1 4757/4885HSD11B1 2691/4885HSD17B10 4363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.