Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185736 | 0.82 | CD44 (0.40) | OPRM1OPRD1OPRK1ABCB1HTR1A | |
| SCHEMBL27359711 | 0.78 | MEN1 (0.49) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL27517559 | 0.78 | MEN1 (0.49) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL27355687 | 0.77 | MEN1 (0.56) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL27361573 | 0.73 | MEN1 (0.60) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL27525446 | 0.73 | KMT2A (0.51) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL23395332 | 0.73 | MEN1 (0.50) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL8474346 | 0.73 | PLAU (0.59) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL27362545 | 0.72 | MEN1 (0.62) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL27528708 | 0.72 | MEN1 (0.53) | OPRM1OPRD1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1515259-A | 4-aminosubstituted-2-substituted-1,2,3,4-tetrahydroquinoline used as CETP inhibitor | �������Զ�˹�Ʒ� | 2004-07-28 | — | — | CN | disclosed |
| CN-1058709-C | Amide compounds for medical treatment | PFIZER (US) | 2000-11-22 | — | — | CN | disclosed |
| CN-1141918-A | Amide compounds for medical treatment | PFIZER (US) | 1997-02-05 | — | — | CN | disclosed |