Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961088 | 0.79 | PLAU (0.47) | PLAUDRD2HTR2AHRH1DRD3 | |
| SCHEMBL10673802 | 0.79 | DRD1 (0.53) | PLAUDRD2DRD3PRMT5 | |
| SCHEMBL23395332 | 0.78 | MEN1 (0.50) | MEN1KMT2AHTR1ADRD2HTR2A | |
| SCHEMBL20909775 | 0.76 | PLAU (0.45) | PLAUMEN1KMT2ADRD2DRD3 | |
| SCHEMBL28752685 | 0.74 | DRD2 (0.49) | MEN1KMT2AHTR1ADRD2HTR2A | |
| SCHEMBL30620400 | 0.74 | HSD17B3 (0.55) | MEN1KMT2AHTR1ADRD2HTR2A | |
| SCHEMBL26161459 | 0.74 | HSD17B3 (0.55) | MEN1KMT2AHTR1ADRD2HTR2A | |
| SCHEMBL27361573 | 0.74 | MEN1 (0.60) | MEN1KMT2AHTR1ADRD2HTR2A | |
| SCHEMBL20884109 | 0.73 | PLAU (0.43) | PLAUMEN1KMT2ADRD2DRD3 | |
| Acetic Acid SCHEMBL6519592 | 0.73 | HDAC3 (0.52) | MEN1KMT2AHTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | disclosed |