Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584056 | 0.84 | NOS3 (0.44) | NOS3NOS1NOS2SORT1KDM4E | |
| SCHEMBL12570324 | 0.83 | NOS3 (0.48) | NOS3NOS1NOS2KDM4EHSD11B1 | |
| Ammonia Solution, Strong SCHEMBL27852366 | 0.82 | NOS3 (0.43) | NOS3NOS1NOS2SORT1KDM4E | |
| SCHEMBL12051660 | 0.77 | NOS3 (0.43) | NOS3NOS1NOS2HSD11B1 | |
| SCHEMBL20089647 | 0.74 | NOS3 (0.40) | NOS3NOS1NOS2 | |
| SCHEMBL26065280 | 0.74 | PTGS2 (0.38) | LMNA | |
| Formamide SCHEMBL22289820 | 0.74 | NOS3 (0.41) | NOS3NOS1NOS2SORT1KDM4E | |
| SCHEMBL22835731 | 0.72 | RBP4 (0.38) | SORT1KDM4E | |
| SCHEMBL22747507 | 0.71 | NOS3 (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL20892192 | 0.68 | CCR1 (0.46) | NOS3NOS2KDM4EHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |