Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27352381 | 0.94 | AVPR2 (0.40) | AVPR2CACNA1BAVPR1AXIAPCYP3A4 | |
| SCHEMBL27361135 | 0.86 | XIAP (0.41) | AVPR2XIAPLMNACHRM2HTR1A | |
| SCHEMBL27431893 | 0.80 | XIAP (0.42) | XIAPLMNAHTR1AMAPTALDH1A1 | |
| SCHEMBL27347889 | 0.79 | AVPR2 (0.54) | AVPR2AVPR1AHTR1ACHRM1SLC6A4 | |
| SCHEMBL27376891 | 0.78 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL6970428 | 0.75 | CYP2D6 (0.43) | AVPR2CACNA1BAVPR1ACYP2D6CYP1A2 | |
| SCHEMBL6969600 | 0.74 | AVPR2 (0.46) | AVPR2CACNA1BAVPR1ACYP2D6CYP1A2 | |
| SCHEMBL27350982 | 0.73 | KDM4E (0.40) | CYP3A4TSHRLMNAADRA1AKCNH2 | |
| SCHEMBL6959648 | 0.70 | AVPR1A (0.42) | AVPR2CACNA1BAVPR1AXIAPTSHR | |
| SCHEMBL6970673 | 0.69 | AVPR2 (0.48) | AVPR2CACNA1BAVPR1ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058710-C | New benzamide derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-11-22 | — | — | CN | disclosed |